Brainmapping.ORG

Dedicated to the communication of news, science, and information of interest to the brain mapping community, and to sharing and promoting the science of brain mapping.

The purpose and goal of brain mapping is to advance the understanding of the relationship between structure and function in the human brain. Scientists in this field seek to gain knowledge of the physical processes that underlie human sensation, attention awareness and cognition. These results are immediately applicable to surgical intervention, to the design of medical interventions and to the treatment of psychological and psychiatric disorders.

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04/19 Large clinical trial to study repurposed drugs to treat COVID-19 symptoms Using an ACTIV master protocol, the trial will focus on potential interventions for mild-to-moderate… 04/16 Experimental antiviral for COVID-19 effective in hamster study MK-4482 shows potential to prevent and treat SARS-CoV-2 infection. … 04/15 NIH closes enrollment in trial comparing COVID-19 treatment regimens Head-to-head trial unlikely to show difference between regimens. … 04/15 NIH-funded COVID-19 testing initiative aims to safely return children to in-person school New RADx-UP research effort combines testing and safety measures in underserved populations. … 04/14 Most differences in DNA binding compounds found at birth in children conceived by IVF not seen in early childhood NIH study results bolster previous studies finding no growth, development differences with IVF. … 04/14 NIH funds new influenza research network Sites will study the natural history, transmission, and pathogenesis of influenza. … 04/13 Study links structural brain changes to behavioral problems in children who snore The findings support early evaluation of children with habitual snoring … 04/13 NIH experts discuss post-acute COVID-19 Symptoms can be wide-ranging in severity and duration, and may affect numerous organ systems. … 04/13 NIH trial of anti-CD14 antibody to treat COVID-19 respiratory disease begins The study will enroll between 300 and 350 hospitalized COVID-19 patients aged 18 years or older at 1… 04/12 Drug testing approach uncovers effective combination for treating small cell lung cancer Scientists targeted a vulnerability in how the cancer cells reproduce. … 12/12 Innovations for Healthy Living - Improving Population Health and Eliminating Health Disparities (R43/R44) Funding Opportunity RFA-MD-17-001 from the NIH Guide for Grants and Contracts. This Fun… 12/12 Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42) Funding Opportunity RFA-MD-17-002 from the NIH Guide for Grants and Contracts. This Fun… 12/12 Novel Analytical Approaches for Metabolomics Data (R03) Funding Opportunity RFA-RM-17-001 from the NIH Guide for Grants and Contracts. The purp… 12/12 Utilizing Health Information Technology to Scale and Spread Successful Practice Models Using Patient-reported Outcomes (R18) Funding Opportunity PA-17-077 from the NIH Guide for Grants and Contracts. This Funding… 12/12 NIH-DoD-VA Pain Management Collaboratory - Coordinating Center (U24) Funding Opportunity RFA-AT-17-002 from the NIH Guide for Grants and Contracts. The purp… 12/12 NIH-DoD-VA Pain Management Collaboratory - Pragmatic Clinical Trials Demonstration Projects (UG3/UH3) Funding Opportunity RFA-AT-17-001 from the NIH Guide for Grants and Contracts. The purp… 12/12 Notice of an Informational Webinar for RFA-NS-17-017 "Frontotemporal Degeneration (FTD) Sequencing Consortium: Discovery, Replication and Validation (UG3/UH3)" Notice NOT-NS-17-010 from the NIH Guide for Grants and Contracts… 12/12 Reminder: NHLBI FY2017 Small Business Topics of Special Interest (TOSI) for the SBIR/STTR Programs Notice NOT-HL-16-479 from the NIH Guide for Grants and Contracts… 12/12 Notice of Intent to Publish a Funding Opportunity Announcement for Conformance with the Manufactured Food Regulatory Program Standards (MFRPS) (U18) Notice NOT-FD-17-001 from the NIH Guide for Grants and Contracts… 12/12 Notice of Extension of the Expiration Date for PA-16-282 Developing New Clinical Decision Support to Disseminate and Implement Patient-Centered Outcomes Research Findings (R18)" Notice NOT-HS-17-005 from the NIH Guide for Grants and Contracts… --- Scientific Meeting » NIMH Livestream Event: Bipolar Disorder in Adolescents and Young Adults In recognition of World Bipolar Day, NIMH hosted a livestream event on bipolar disorder in adolescen… --- Blog Post » One Year of Rapid Acceleration of Diagnostics, and Anticipating New Challenges In this jointly written Director?s Message, leadership from across NIH describes one year of progres… --- Science News » NIMH?s Dr. Andrea Beckel-Mitchener Named Deputy Director of NIH BRAIN Initiative Andrea Beckel-Mitchener, Ph.D., has been named deputy director of the trans-NIH Brain Research throu… --- Scientific Meeting » Virtual Workshop: Integrating Genomics with Dimensional and Transdiagnostic Approaches to Advance Mental Health Research This workshop aims to highlight opportunities and challenges related to integrating genomic informat… --- Video » The NIMH Director?s Innovation Speaker Series: Advancing Therapies for Central Nervous System Disorders On April 15, 2021, Beverly Davidson, Ph.D., was the guest speaker for the NIMH Director?s Innovation… --- Video » NIMH Expert Dr. Mary Rooney Discusses Bipolar Disorder in Adolescents and Young Adults In recognition of World Bipolar Day, NIMH hosted a livestream event on bipolar disorder in adolescen… --- Scientific Meeting » The NIMH Director?s Innovation Speaker Series: Advancing Therapies for Central Nervous System Disorders On April 15, 2021, Beverly Davidson, Ph.D., was the guest speaker for the NIMH Director?s Innovation… --- Scientific Meeting » The NIMH Director?s Innovation Speaker Series: What the Eyes Don?t See: A Story of Crisis, Resistance, and Hope in an American City Mona Hanna-Attisha, M.D., M.P.H., the pediatrician and scientist who exposed the lead water crisis i… --- Blog Post » One Year In: COVID-19 and Mental Health In this message, Dr. Gordon highlights what we know about Americans? mental health after one year of… --- Science News » NIMH Director?s Statement: Our Commitment to Ending Structural Racism in Biomedical Research In this statement, NIMH Director Dr. Joshua Gordon reaffirms his commitment to dismantling structura…		04/21 Brain Cancer Diagnostics Market 2021 Top Countries Data with Future Scope, Market Size, Definition, Opportunities with Strategic Growth and Top Key Players Analysis and Forecasts to 2026 … CT Scan (SPECT) ? Spinal Tap ? Magnetic Resonance Imaging (MRI) … 04/21 Pharmacist-led programs help prevent medication harm in older adults in care facilities An analysis of published studies indicates that pharmacist-led efforts can reduce medication-related… 04/20 New study says autism develops differently depending on gender … in boys. Using a functional magnetic-resonance imaging to examine brain a… 04/20 Our attention is captured by eye-glance Researchers (UNIGE) looked at the way we process human gaze, focusing on the estimation of the tempo… 04/20 Research finds autism develops differently in girls than boys … . Pelphrey and colleagues used functional magnetic resonance imaging (fMRI) to examine brai… 04/20 New implantable tool images brain activity in 3D … used techniques such as functional magnetic resonance imaging, but this method cannot reco… 04/20 Human land use wasn't always at nature's expense Nearly three-quarters of Earth's land had been transformed by humans by 10,000BC, but new research s… 04/20 Autism Develops Differently in Girls Than Boys, New Research Suggests … . Pelphrey and colleagues used functional magnetic-resonance imaging (fMRI… 04/20 Prescription Medication Abuse Nearly Equals Alcohol Abuse Among Unemployed During COVID-19 Pandemic Forty Percent of Symptomatic Prescription Drug Abusers Fall Into Moderate or High -Risk Add… 04/20 Gold digger: Neural networks at the nexus of data science and electron microscopy Researchers at the Max Planck Florida Institute for Neuroscience used machine learning to develop a … 04/20 New findings suggest organ tissues become increasingly immune throughout life University of Minnesota Medical School researchers have offered new ways to think about the immune s… 04/20 Astronauts' mental health risks tested in the Antarctic Astronauts who spend prolonged time alone in space face mental health stressors like loneliness, iso… 04/20 Sexual receptivity and rejection may be orchestrated by the same brain region Mice study offers a new working hypothesis on how a small brain region in the hypothalamus may contr… 04/20 Fast brainwave oscillations identify and localize epileptic brain Professor Bin He's team at Carnegie Mellon University, in collaboration with the Mayo Clinic, has di… 04/20 A gene finding links severe canine juvenile epilepsy to mitochondrial dysfunction In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy re… 04/20 Is social media use a potentially addictive behaviour? Frequent use of social media may not amount to the same as addiction, according to research at the U… 04/19 Study reveals new clues to sex differences in autism … brain imaging technology called functional magnetic resonance imaging, the researchers fou… 04/17 Study suggests autism develops differently in girls than boys … among boys. Researchers used functional magnetic-resonance imaging (fMRI)… 04/16 Study sheds light on how autism manifests in the brains of girls … . Pelphrey and colleagues used functional magnetic-resonance imaging (fMRI… 04/15 Are Humans More Sensitive To Screams From Sex Than From Fear? … brains scanned inside a functional Magnetic Resonance Imaging (fMRI) machine while they li… 12/16 Drumming makes your brain more efficient Playing the drums requires coordination between all four limbs. A new study asks whether, over years… 12/06 Repairing leaky blood-brain barrier may rejuvenate brain function New research in mice suggests that a leaky blood-brain barrier can accelerate brain aging, and that … 12/04 New MRI scans reveal brain features of depression Using new types of MRI, scientists have observed features of the blood-brain barrier and activity in… 11/25 Everything you need to know about choline Choline is an essential nutrient that humans need for neurodevelopment and many other bodily functio… 11/27 Brain Atrophy in Natalizumab ?treated Patients with Multiple Sclerosis: A 5?year Retrospective Study CONCLUSIONOur results contribute to the increasing knowledge of PBVCs in natalizumab ?treated MS pat… 11/22 Femoral Neuropathy Following Transfemoral Neuroendovascular Procedures. An Analysis of a Prospective Registry CONCLUSIONSFemoral neuropathy is a rare occurrence following transfemoral neuroendovascular procedur… 11/22 Ultrasound, Clinical, and Electrophysiological Findings in Persistent Carpal Tunnel Syndrome CONCLUSIONOur data show significant functional disability, axonal nerve damage, and scar tissue form… 11/22 Impact of Intraoperative Hyperglycemia on Brain Structures and Volumes CONCLUSIONSThis study found no effect of intraoperative hyperglycemia on postoperative brain structu… 11/20 Early Phase PIB ?PET as a Surrogate for Global and Regional Cerebral Blood Flow Measures CONCLUSIONEarly PIB uptake has the potential to effectively serve as a surrogate for global and regi… 11/19 Diffusion Tensor Imaging of the Superior Thalamic Radiation and Cerebrospinal Fluid Distribution in Idiopathic Normal Pressure Hydrocephalus CONCLUSIONSCombined microstructural (DTT) and macrostructural (ventricular volume) changes is a prom… 11/19 Simulation and Experimental Characterization of Lateral Imaging Resolution of Ultrasound Systems and Assessment of System Suitability for Acoustic Optic Nerve Sheath Diameter Measurement CONCLUSIONAccording to our study, both systems are suitable for ultrasound OSND measurement. (Source… 11/07 Microvessels may Confound the ?Swallow Tail Sign? in Normal Aged Midbrains: A Postmortem 7 T SW?MRI Study CONCLUSIONBoth iron deposits and microvessels contribute to the hyposignal surrounding nigrosome 1 i… 11/07 Clinical, Sonographic, and Electrophysiologic Longitudinal Features of Chronic Inflammatory Demyelinating Polyneuropathy CONCLUSIONNerve ultrasound can be used as a method to objectify the long ?term disease course in CID… 11/05 What Threshold Defines Penumbral Brain Tissue in Patients with Symptomatic Anterior Circulation Intracranial Stenosis: An Exploratory Analysis CONCLUSIONSA target mismatch profile usingTmax > 6 seconds may define tissue at risk in patient… 11/05 White Matter Microstructure Correlates with Memory Performance in Healthy Children: A Diffusion Tensor Imaging Study CONCLUSIONSSignificant correlations between DTI parameter values and CMS indices in multiple WM trac… 10/31 Dr. Leon D. Prockop (1934 ?2018), Founding Editor?in?Chief, Journal of Neuroimaging Journal of Neuroimaging,Volume 28, Issue 6, Page 555-555, November/December 2018. (Source: Journal o… 10/31 Issue Information Journal of Neuroimaging,Volume 28, Issue 6, Page 551-554, November/December 2018. (Source: Journal o… 10/30 Pediatric Congenital Cerebrovascular Anomalies Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/29 Diffusely Abnormal White Matter, T2 Burden of Disease, and Brain Volume in Relapsing ?Remitting Multiple Sclerosis Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/24 Assessing the Relationship between Atherosclerotic Cardiovascular Disease Risk Score and Carotid Artery Imaging Findings Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/15 The Role of Diffusion Tensor Imaging in Detecting Hippocampal Injury Following Neonatal Hypoxic ?Ischemic Encephalopathy Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/11 Neuroimaging in Psychiatric Disorders: A Bibliometric Analysis of the 100 Most Highly Cited Articles Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/09 Functional Brain Network Changes Following Use of an Allostatic, Closed ?Loop, Acoustic Stimulation Neurotechnology for Military?Related Traumatic Stress Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/09 Arterial Spin Labeling MRI to Measure Cerebral Blood Flow in Untreated Ischemic Stroke Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/07 Gliosarcoma: Neuroimaging and Immunohistochemical Findings Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/07 MRI ?Guided High?Intensity Focused Ultrasound as an Emerging Therapy for Stroke: A Review Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/03 Brief Computer ?Based Information Processing Measures are Linked to White Matter Integrity in Pediatric?Onset Multiple Sclerosis Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 09/19 Teriflunomide's Effect on Glia in Experimental Demyelinating Disease: A Neuroimaging and Histologic Study Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 09/18 Multicenter Measurements of T1 Relaxation and Diffusion Tensor Imaging: Intra and Intersite Reproducibility Journal of Neuroimaging, EarlyView. (Source: Journal of Neuroimaging)… 10/30 Automated lesion detection on MRI scans using combined unsupervised and supervised methods Background: Accurate and precise detection of brain lesions on MR images (MRI) is paramount for accu…
More NIH News...

At left: Diffusion Imaging, Diffusion Tensor Imaging and Fiber Tracking

Recent advances in magnetic resonance research have opened up new opportunities for gathering functional information about the brain. The development of diffusion imaging and diffusion tensor imaging (DTI) has offered the possibility to go beyond anatomical imaging and study tissue structure at a microscopic level in vivo. Currently, DTI provides an invaluable tool for the study and diagnosis of white-matter diseases. Increasing research focus has been placed on studying neuronal connectivity. An important application of DTI is fiber tracking, which allows elucidation of white-matter tracts. Combined with fMRI, information about white-matter tracts reveals important information about neurocognitive networks, and may improve our understanding of brain function. Recently, the potential of applying SENSE to DTI was demonstrated at 3.0 Tesla to improve acquisition speed and image quality. These studies have demonstrated the feasibility of fast fiber tracking in the human brain. Future research will concentrate on improving the accuracy and robustness of the technique, as well as enhanced visualization of the white fiber tracts in three dimensions.dipl. phys. Thomas Järmann, dipl. inf. ETH Philipp Stämpfli, Dr. Klaas Prüssmann, Prof. Dr. Peter Boesiger

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At left: Diffusion Imaging, Diffusion Tensor Imaging and Fiber Tracking